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Avodart is for use by men only.

Read this patient information before you start taking Avodart (Dutasteride) and each time you get a refill. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or your treatment.

What is Avodart?

Avodart (Dutasteride) is a prescription medicine that contains dutasteride. This medication is used to treat the symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate to:
  • Improve symptoms
  • Reduce the risk of acute urinary retention (a complete blockage of urine flow)
  • Reduce the risk of the need for BPH-related surgery

    Who should NOT take Avodart?

    Do Not Take Avodart (Dutasteride) if you are:

  • pregnant or could become pregnant. This drug may harm your unborn baby. Pregnant women should not touch Avodart Capsules. If a woman who is pregnant with a male baby gets enough Dutasteride in her body by swallowing or touching Avodart, the male baby may be born with sex organs that are not normal. If a pregnant woman or woman of childbearing potential comes in contact with leaking this medicine in capsules, the contact area should be washed immediately with soap and water.
  • a child or a teenager.
  • allergic to dutasteride or any of the ingredients in Avodart. See the end of this leaflet for a complete list of ingredients in Avodart capsules.
  • allergic to other 5-alpha-reductase inhibitors, for example, Proscar (Finasteride) tablets.

    What should I tell my healthcare provider before taking Avodart?

    Before you take Avodart (Dutasteride), tell your healthcare provider if you:

  • have liver problems

    Tell your healthcare provider (doctor or pharmacist) about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Avodart and other medicines may affect each other, causing side effects. This medication may affect the way other medicines work, and other medicines may affect how Avodart works.

    Know the medicines you take. Keep a list of them to show your healthcare provider and pharmacist when you get a new medicine.

    How should I take Avodart?

  • Take 1 Avodart capsule once a day.
  • Swallow Avodart (Dutasteride) capsules whole. Do not crush, chew, or open Avodart capsules because the contents of the capsule may irritate your lips, mouth, or throat.
  • You can take this drug with or without food.
  • If you miss a dose, you may take it later that day. Do not make up the missed dose by taking 2 doses the next day.

    What should I avoid while taking Avodart?

  • You should not donate blood while taking Avodart (Dutasteride) or for 6 months after you have stopped Avodart. This is important to prevent pregnant women from receiving this medicine through blood transfusions.

    What are the possible side effects of Avodart?

    Avodart (Dutasteride) may cause serious side effects, including:

  • Rare and serious allergic reactions, including: swelling of your face, tongue, or throat; serious skin reactions, such as skin peeling.
    Get medical help right away if you have these serious allergic reactions.
  • Higher chance of a more serious form of prostate cancer.

    The most common side effects of Avodart include:
  • trouble getting or keeping an erection (impotence)
  • a decrease in sex drive (libido)
  • ejaculation problems
  • enlarged or painful breasts. If you notice breast lumps or nipple discharge, you should talk to your healthcare provider.

    Avodart (Dutasteride) has been shown to reduce sperm count, semen volume, and sperm movement. However, the effect of Avodart on male fertility is not known.

    Prostate Specific Antigen (PSA) Test: Your healthcare provider may check you for other prostate problems, including prostate cancer before you start and while you take Avodart. A blood test called PSA (prostate-specific antigen) is sometimes used to see if you might have prostate cancer. This medication will reduce the amount of PSA measured in your blood. Your healthcare provider is aware of this 822 effect and can still use PSA to see if you might have prostate cancer. Increases in 823 your PSA levels while on treatment with Avodart (even if the PSA levels are in the normal range) should be evaluated by your healthcare provider.

    Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

    These are not all the possible side effects with Avodart. For more information, ask you healthcare provider or pharmacist.

    Call your doctor for medical advice about side effects. You may report side effects to US FDA.

    How should I store Avodart?

  • Store Avodart (Dutasteride) capsules at room temperature (59°F to 86°F or 15°C to 30°C).
  • Avodart capsules may become deformed and / or discolored if kept at high temperatures.
  • Do not use this drug if your capsules are deformed, discolored, or leaking.
  • Safely throw away medicine that is no longer needed.

    Keep Avodart and all medicines out of the reach of children.

    Medicines are sometimes prescribed for purposes other than those listed in a patient leaflet. Do not use Avodart for a condition for which it was not prescribed. Do not give this medicine to other people, even if they have the same symptoms that you have. It may harm them.

    This patient information leaflet summarizes the most important information about Avodart (Dutasteride). If you would like more information, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about this medication that is written for health professionals.

    What are the ingredients in Avodart?

    Active ingredient: dutasteride.
    Inactive ingredients: butylated hydroxytoluene, ferric oxide (yellow), gelatin (from certified BSE-free bovine sources), glycerin, mono-di-glycerides of caprylic / capric acid, titanium dioxide, and edible red ink.

    How does Avodart work?

    Prostate growth is caused by a hormone in the blood called dihydrotestosterone (DHT). Dutasteride lowers DHT production in the body, leading to shrinkage of the enlarged prostate in most men. While some men have fewer problems and symptoms after 3 months of treatment with Avodart, a treatment of period of at least 6 months is usually necessary to see if Avodart (Dutasteride) will work for you.

    Manufactured and distributed by GlaxoSmithKline pharmaceutical company and its divisions.

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